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Preview of Seq Structure Convergence

Seq Structure Convergence

Do a sequence-trained (ESM-2/CARP) and a structure-trained (ProteinMPNN/ESM-IF1) protein foundation model converge beyond their shared training target? A cross-modality test of the Platonic Representation Hypothesis using CKA/SVCCA/mutual-kNN with permutation nulls and amino-acid identity…

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